Anti-depressant plus alcohol question...?

I am currently taking effexor xr and the directions and bottle say not to use alcohol while on this medication. I am only a social drinker and so should I just skip the daily dosage when I plan to drink or continue taking it as prescribed? Surely just skipping one day wouldn't hurt right? And why can't you even drink at all while using it? It doesn't make sense to me...It's not a narcotic so I don't see why not? Anyone have any advice or suggestions? Thanks in advance.